Menthol Fine Flakes  

Peppermint leaves carry menthol-rich volatile oils as well as tannins and bitters. Research has revealed this triad of compounds form a digestion improving cocktail that only nature could devise. Its oils sedate unhappy digestive tract nerves and reduce the shipment of nausea impulses to the brain. The tannins reduce any inflammation that might be present in the gut. The bitters increase the production. The cytotoxicity associated with essential oil has been attributed to various effects such as the production of reactive species, change in fluidity and membrane permeability, tubulin polymerization, imbalance in ion transport, and inhibition of protein function.             

Peppermint oil finds wide application in the flavoring of chewing gums, sugar confectionery, ice creams, desserts, baked goods, tobacco, and alcoholic beverages. It is also frequently employed in the flavoring of pharmaceutical and oral preparations.

COMMON USAGE

·        Promotes digestion

·        Prevents dental problems

·        Beneficial for nail care

·        Reduces headaches

·        Acts as strain buster

·        Relieves twitches

·        Treats urinary infection

·        Cures respiratory ailments

·        Reduces different types of pain

·        Strengthens immunity

·        Promotes blood circulation

·        Best hair care remedy

·        Good to cure skin problems

Ingredients:

*The Menthol is in Crystalized form.

TOXICOLOGICAL INFORMATION

Safety Summary

·        Hazards May be choleretic; mucous membrane irritation.

·        Contraindications (all routes): Cardiac fibrillation, G6PD deficiency. Do not apply to or near the face of infants or children.

·        Contraindications (oral): Cholestasis.

·        Cautions (oral): Gastroesophageal reflux disease.

Safety advice

Cornmint oil should be avoided altogether in cases of cardiac fibrillation and by people with a G6PD deficiency. This is a fairly common inheritable enzyme deficiency, particularly in people of Chinese, West African, Mediterranean or Middle Eastern origin. People with G6PD deficiency will typically have abnormal blood reactions to at least one of the following drugs, or will have been advised to avoid them: antimalarials, sulfonamides, chloramphenicol, streptomycin, aspirin. The pulegone and menthofuran content is not high enough to require restriction in our opinion.

Organ Specific Effects

·        Adverse skin reactions: Undiluted cornmint oil was not irritating to rabbit, pig or mouse skin; tested at 8% on 25 volunteers it was neither irritating nor sensitizing. It is non-phototoxic.

·        Cardiovascular effects: Cornmint oil inhibits platelet aggregation, but only very weakly. Peppermint confectionery and mentholated cigarettes have been responsible for cardiac fibrillation in patients prone to the condition who are being maintained on quinidine, a stabilizer of heart rhythm. Bradycardia has been reported in a person addicted to menthol cigarettes.

·        Neonatal toxicity: Menthol can cause neonatal jaundice in babies with a deficiency of the enzyme glucose-6-phosphate dehydrogenase. Usually, menthol is detoxified by a metabolic pathway involving G6PD. When babies deficient in this enzyme were given a menthol-containing dressing for their umbilical stumps, menthol accumulated in their bodies

·        Gastrointestinal toxicology: Both peppermint oil and menthol are choleretic and therefore cornmint oil should not be taken in oral doses by people with cholestasis. Since peppermint oil relaxes the lower esophageal sphincter, oral administration of cornmint oil may cause discomfort in cases of GERD.

·        Hepatotoxicity: Oral doses of menthol or menthone above 200 mg/kg for 28 days produced signs of liver toxicity in rats. Menthofuran is toxic to both liver and lung tissue in mice. In rats, oral dosing with menthofuran caused hepatotoxicity, as demonstrated by changes in blood levels of enzyme markers for liver disease. Cornmint oil is unlikely to cause liver problems at the doses used in aromatherapy.

Systemic Effects

·        Acute toxicity, human: A proprietary menthol-containing oil was reported to cause incoordination, confusion and delirium when 5 mL of the product was inhaled over a long time period. Nasal preparations containing menthol can cause apnea and collapse in infants following instillation into the nose.

·        Acute toxicity, animal: Cornmint oil acute oral LD50 in rats 1.24 g/kg; acute dermal LD50 in rabbits >5 g/kg.

·        Skin corrosion/irritation: May be irritating to skin.

·        Serious eye damage/irritation: May be irritating to eyes. Prompt rinsing and removal of the substance will avoid damage.

·        Respiratory sensitization: Not applicable under normal use.

·        Germ cell mutagenicity: Not specified

·        Carcinogenicity: Not listed As Carcinogen

·        Reproductive toxicity: Not specified

·        STOT-single exposure: Not specified

·        STOT-related exposure: Not specified

ECOLOGICAL INFORMATION

·        Ecotoxicity Aquatic hazard acute category 2, Aquatic hazard chronic category 2.

·        Persistence & Biodegradability No additional data available.

·        PBT Assessment Results No additional data available

·        Persistence and degradability Biodegradation is expected

·        Bio-accumulative potential Bioaccumulation is unlikely

·        Mobility in soil Unknown

Do not discharge into the environment, especially not into waterways, sewers and the environment.