EU_Declaration25.pdf
Appearance and Physical Characteristics Crystalized form of Menthol and Specific as per Customer Requireme Read More
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Appearance and Physical
Characteristics |
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Crystalized form of Menthol
and Specific as per Customer Requirement |
The process of formulating Menthol essential
oil has begun when the menthol flowers and leaves are not enough matured. This
is the time when essential oil content is at its peak. Manufacturers made it
usable through steam distilled methodology where the essence of menthol is
prepared at apt temperature.
This mint plant is found in
various parts of Europe, Asia and North America. Its common names include Field
Mint, Wild Mint or Corn Mint; however, it is better known by its scientific
name Mentha arvensis. The leaves of this herbal plant have a fresh minty flavor
and are used for culinary and medicinal purposes. The essential oil extracted
from the leaves also has many uses.
These herbal plants have been
used by humans for approximately 2000 years. It is believed that these plants
were first cultivated in Europe during ancient times. However, Japan started
cultivating these mint plants for commercial purposes in the late nineteenth
century. Countries like China and Japan used them for various medicinal purposes.
Later they were introduced to India where they are still known as Pudina.
Peppermint leaves
carry menthol-rich volatile oils as well as tannins and bitters.
Research has revealed this triad of compounds form a digestion improving
cocktail that only nature could devise. Its oils sedate
unhappy digestive tract nerves and reduce the shipment of nausea
impulses to the brain. The tannins reduce any inflammation that
might be present in the gut. The bitters increase the production. The
cytotoxicity associated with essential oil has been attributed to various
effects such as the production of reactive species, change in fluidity and
membrane permeability, tubulin polymerization, imbalance in ion transport, and
inhibition of protein function.
Peppermint oil finds wide
application in the flavoring of chewing gums, sugar confectionery, ice creams,
desserts, baked goods, tobacco, and alcoholic beverages. It is also frequently
employed in the flavoring of pharmaceutical and oral preparations.
COMMON USAGE
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Promotes
digestion
·
Prevents
dental problems
·
Beneficial
for nail care
·
Reduces
headaches
·
Acts
as strain buster
·
Relieves
twitches
·
Treats
urinary infection
·
Cures
respiratory ailments
·
Reduces
different types of pain
·
Strengthens
immunity
·
Promotes
blood circulation
·
Best
hair care remedy
·
Good
to cure skin problems
Ingredients:
*The Menthol is in Crystalized
form.
TOXICOLOGICAL
INFORMATION
Safety Summary
·
Hazards May be choleretic; mucous
membrane irritation.
·
Contraindications (all routes): Cardiac
fibrillation, G6PD deficiency. Do not apply to or near the face of infants or
children.
·
Contraindications (oral): Cholestasis.
·
Cautions (oral): Gastroesophageal reflux
disease.
Organ Specific Effects
·
Adverse skin reactions: Undiluted
cornmint oil was not irritating to rabbit, pig or mouse skin; tested at 8% on
25 volunteers it was neither irritating nor sensitizing. It is non-phototoxic.
·
Cardiovascular effects: Cornmint oil inhibits
platelet aggregation, but only very weakly. Peppermint confectionery and
mentholated cigarettes have been responsible for cardiac fibrillation in
patients prone to the condition who are being maintained on quinidine, a
stabilizer of heart rhythm. Bradycardia has been reported in a person addicted
to menthol cigarettes.
·
Neonatal toxicity: Menthol can cause
neonatal jaundice in babies with a deficiency of the enzyme glucose-6-phosphate
dehydrogenase. Usually, menthol is detoxified by a metabolic pathway involving
G6PD. When babies deficient in this enzyme were given a menthol-containing
dressing for their umbilical stumps, menthol accumulated in their bodies
·
Gastrointestinal toxicology: Both
peppermint oil and menthol are choleretic and therefore cornmint oil should not
be taken in oral doses by people with cholestasis. Since peppermint oil relaxes
the lower esophageal sphincter, oral administration of cornmint oil may cause
discomfort in cases of GERD.
·
Hepatotoxicity: Oral doses of menthol or
menthone above 200 mg/kg for 28 days produced signs of liver toxicity in rats.
Menthofuran is toxic to both liver and lung tissue in mice. In rats, oral
dosing with menthofuran caused hepatotoxicity, as demonstrated by changes in
blood levels of enzyme markers for liver disease. Cornmint oil is unlikely to
cause liver problems at the doses used in aromatherapy.
Systemic Effects
·
Acute toxicity, human: A proprietary
menthol-containing oil was reported to cause incoordination, confusion and
delirium when 5 mL of the product was inhaled over a long time period. Nasal
preparations containing menthol can cause apnea and collapse in infants
following instillation into the nose.
·
Acute toxicity, animal: Cornmint oil
acute oral LD50 in rats 1.24 g/kg; acute dermal LD50 in rabbits >5 g/kg.
·
Skin corrosion/irritation: May be irritating to
skin.
·
Serious eye damage/irritation: May be irritating
to eyes. Prompt rinsing and removal of the substance will avoid damage.
·
Respiratory sensitization: Not applicable under
normal use.
·
Germ cell mutagenicity: Not specified
·
Carcinogenicity: Not listed As Carcinogen
·
Reproductive toxicity: Not specified
·
STOT-single exposure: Not specified
·
STOT-related exposure: Not specified
ECOLOGICAL
INFORMATION
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Ecotoxicity Aquatic hazard acute category 2,
Aquatic hazard chronic category 2.
·
Persistence & Biodegradability No additional
data available.
·
PBT Assessment Results No additional data
available
·
Persistence and degradability Biodegradation is
expected
·
Bio-accumulative potential Bioaccumulation is
unlikely
·
Mobility in soil Unknown
Do not discharge into the
environment, especially not into waterways, sewers and the environment.
