Celery Oil  

A. graveolens is a biennial plant locally known as “Karafs”, belonging to family Apiaceae. Various parts of A. graveolens are used in hepatic and spleen disorders, brain disorders, body pain, and sleep disturbances. Celery has been used in the traditional system of medicine to treat spasm and stomach problems and as diuretic, laxative, and sedative. It is used as heart tonic to lower the blood pressure in African traditional medicine in Trinidad and Tobago. There is also a report to the use of celery in joint problems. The celery seed is well known as libido stimulant in the traditional system of medicine due to its protective role against the sodium valproate in testes and amplification of the sperm profile. It also increases the secretion of breast milk.

Celery Essential Oil in Pharma

Celery also stimulates semen production and relieves offensive breath. Al-Rajhi said that one should avoid eating celery if he/she fears that he/she might suffer a scorpion sting. A. graveolens is a big source phenolic compounds, which provides a good source of antioxidants. The antioxidant activity of Karafs leaf was investigated (by scavenging of the 1,1-diphenyl 2-picrylhydrazyl [DPPH] radical activity) and found to be a strong natural antioxidant by inhibiting oxidant process. It may be attributed to its antioxidant constituents including L-tryptophan and derivatives of methoxy-phenyl chromenone. The seed oil of the celery has a strong larvicidal, adulticidal, and repellent activity against the Aedes aegypti larva, the vector of dengue hemorrhage fever. In another study, the mosquito repellent activity of celery oil (with 5% vanillin) was found better repellent activity than a number of commercially used repellent.

Essence of Celery Essential Oil

Celery is valued not only for its nutritional properties but also for the distinctive aroma which it owes to the presence of phthalide-rich essential oil. Thus, Apium graveolens is widely used as a spice and flavoring ingredient in food products. The current trend toward the use of natural preservatives triggered research on antibacterial, antifungal, and antioxidant properties of volatile oils, including celery.

COMMON USAGE

·        Lowers High Blood Pressure

·        Cancer Prevention

·        Provides Calcium

·        Pain Reliever

·        Mosquito Repellant

·        Nerve Calming Effects

·        Prevents Gout and Arthritis

·        Help in energy production and antioxidant defense

·        Joint Problems

·        Reduces Muscle Spasms

·        Anti-Bacterial Properties

·        Can help individuals sleep

·        Blood Pressure

·        Celery seeds can assist in red blood cell formation

·        Lowers Cholesterol

·        Kidney Stone

Ingredients:

TOXICOLOGICAL INFORMATION

Safety Summary

·        Hazards: Skin sensitization if oxidized.

·        Cautions: Old or oxidized oils should be avoided.

Organ-specific effects

·        Adverse skin reactions: Undiluted celery seed oil was not irritating either to rabbits or to mice; tested at 4% on 25 volunteers it was neither irritating nor sensitizing. It is non-phototoxic. Autoxidation products of (þ)- limonene can cause skin sensitization.

·        Reproductive toxicity The low developmental toxicity of (þ)- limonene in rabbits and mice suggests that celery seed oil is not hazardous in pregnancy.

Systemic effects

·        Acute toxicity Celery seed oil acute oral LD50 in rats >5 g/kg; acute dermal LD50 in rabbits>5 g/kg.

·        Antioxidant/pro-oxidant activity Celery seed oil showed moderate antioxidant activity as a DPPH radical scavenger and high activity in the aldehyde/carboxylic acid assay.

·        Carcinogenic/anticarcinogenic potential Celery seed oil dose-dependently inhibited aflatoxin B1-induced adducts in calf thymus DNA, in the presence of rat liver microsomes. Celery seed oil significantly induced glutathione S-transferase activity in mouse tissues. (þ)-Limonene displays anticarcinogenic activity . Sedanolide and 3-butyl phthalide reduced the incidence of forestomach cancer in mice.

ECOLOGICAL INFORMATION

·        Toxic to aquatic organisms, may cause long-term adverse effects environment. Avoid any pollution of ground, surface or underground water.

·        Persistence & degradability Biodegradability: no degradability data is available; the substance is considered as not degrading quickly.

·        Bioaccumulation Potential No additional data available.

·        Mobility in soil No additional data available.

·        Results of PBT and vPvB Assessment No additional data available.