MSDS-Nutmeg1.pdf
Botanical Name: Myristica fragrans Common name: Nutmeg Read More
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Botanical Name: |
Myristica fragrans |
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Common name: |
Nutmeg |
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Plant family: |
Myristicaceae |
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Genus: |
Myristica |
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Appearance/Color: |
Colorless to Pale yellow liquid with thin consistency |
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Odor: |
Scent has soft, spicy, and woody with a slightly musky note; with a medium aroma at a middle note. |
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Blends With: |
Petitgrain, Lavender, Geranium, Orange, Clary Sage, Rosemary and other Spice Oils. |
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Origin: |
India |
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Source: |
Kernels |
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Method of Extraction: |
Hydro-Distillation |
Nutmeg seed is encased in a mottled yellow, edible fruit which is in the approximate size and shape of a small peach. The fruit depicts a net-like, bright red covering over the seed when splited in to half. The aril is collected, dried and sold as mace. Under the aril is a dark shiny nut-like pit, and inside it is an oval shaped seed which is called the nutmeg. Nutmegs are usually sold without the mace.
Until the mid-19th century, the small island group of the Banda Islands, which are also known under the name "Spice Islands," was the only location of the production of the spices nutmeg and mace in the world. The Banda Islands are situated in the eastern part of Indonesia, in the province of Maluku. They consist of eleven small volcanic islands, called Neira, Gunung Api, Banda Besar, Rhun, Ai, Hatta, Syahrir, Karaka, Manukan, Nailaka and Batu Kapal, with a total approximate land area of 8,150 hectares.
Nutmeg is a delicate, slightly sweet spice that is widely used in cuisines around the world. The tree is also highly valued because of the essential oils derived from the tree and leaves, and nutmeg butter is also a popular derivative food that packs a healthy punch. The essential oils from nutmeg steam extract are highly beneficial to health and are frequently used in alternative and herbal medicine.
Nutmeg is a popular spice that is widely used in world famous cuisines. The essential oils obtained from nutmeg steam extract are very much beneficial to health and are frequently used in alternative and herbal medicine. Nutmeg oil is traditionally used with honey to improve digestion and also in the treatment of chronic diarrhoea, constipation, indigestion gastroenteritis and nausea. It is a digestive system regulator.
Nutmeg India Essential oil in Pharma
Nutmeg oil is used with other aromatic oils in massages for treatment of chronic soft muscle pain.
It exudes a warming, relaxing, spicy aroma that energizes mind as well as deeply soothe senses. Its ability to cure muscle contractions and pains owns to the sedative nature. For this reason, Nutmeg essential oil is commonly featured in medicinal and aroma therapeutic remedies for treating muscular aches and cramps, insomnia, and anxiety. Nutmeg oil is also known as an effective anti-inflammatory agent. It is industrially used in perfumeries and pharmaceuticals.
Nutmeg oil can also improve regulation of heart and blood circulation in general and uplifting the state of mind and its stimulation after fainting.
Essence of Nutmeg India Essential oil
Nutmeg essential oil has extensive uses in food industry for preparing baked, beverages, syrups and sweets. The sweet spicy flavour aids for this application.
Even beauty products like creams and gels are made up of the oil. Toothpastes, cough syrups, and many more, the use-list of the nutmeg oil is simply endless.
Nutmeg oil has been known to be a tonic for the regulation of the reproductive system – regulating periods and relieving frigidity in women and aiding in the treatment of impotence in men. It is also known to help in childbirth by strengthening muscles to improve contractions.
Nutmeg oil is used to relieve patients of rheumatic ailments from severe pain and is also used as an emergency painkiller in tooth aches. nutmeg oil is a best choice.
Nutmeg oil is a best choice against nervous problems, vomiting, nausea, kidney problems, diarrhoea, abdominal pain, bad breath.
It is also a popular ingredient in cosmetics as well as personal care products, especially within men's grooming and oral health care. And is reputed for its anti-inflammatory, antimicrobial, antioxidant, carminative, and cleansing properties.
COMMON USAGE
· Relieves Pain
· Promotes Digestion
· Improves Brain Health
· Detoxifies the Body
· Oral Health
· Treats Insomnia
· Treats Leukemia
· Skin Care
· Regulates Blood Pressure
Ingredients:
|
S.No |
Key Constituents |
Strength (%) |
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1 |
Sabinene |
42.0–57.0 |
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2 |
a-Pinene |
1.6–12.6 |
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3 |
b-Pinene |
7.8–12.1 |
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4 |
Terpinen-4-ol |
3.0–6.4 |
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5 |
g-Terpinene |
1.7–4.7 |
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6 |
(þ)-Limonene |
2.9–4.4 |
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7 |
a-Terpinene |
0.8–4.2 |
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8 |
b-Myrcene |
2.2–3.4 |
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9 |
p-Cymene |
0.7–3.2 |
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10 |
E)-Sabinene hydrate |
0.3–2.4 |
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11 |
Terpinolene |
1.4–1.7 |
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12 |
Elemicin |
1.2–1.4 |
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13 |
a-Thujene |
1.2 |
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14 |
(Z)-p-Piperitol |
0.4–0.2 |
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15 |
Myristicin |
0.5–0.9 |
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16 |
Safrole |
0.1–0.5 |
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17 |
Methyl eugenol |
0.1–0.2 |
TOXICOLOGICAL INFORMATION
Safety Summary
· Hazards: Basing on safrole and methyl eugenol content it is potentially carcinogenic, and psychotropic in high doses.
· Cautions: No information found.
Safety advises
It is recommended maximum dermal use of 0.8% for the Indian oil based on 3.3% safrole and 1.2% methyl eugenol content, and 5% for the Indian oil based on 0.5% safrole and 0.2% methyl eugenol content, applying dermal limits of 0.05% and 0.02% for safrole and methyl eugenol, respectively is recommended. Maximum daily oral doses are based on 0.025 mg/kg for safrole and 0.01 mg/kg for methyl eugenol.
Organ Specific Effects
· Adverse skin reaction: Undiluted nutmeg oil was moderately irritating to rabbits; tested at 2% on 25 volunteers it was neither irritating nor sensitizing.
· Neurotoxicity: Since sixteenth century, Nutmeg is well known for its narcotic, intoxicating properties since the sixteenth century.
· Reproductive toxicity: Nutmeg oil is tested at up to 260 mg/kg to pregnant rats for 10 consecutive days, up to 560 mg/kg to pregnant mice for 10 consecutive days, and up to 600 mg/kg to pregnant hamsters for five consecutive days and it has been observed that no effect on implantation or on maternal or fetal survival is noticed; no teratogenic effect was observed in comparison with controls (NTIS 1976). Sabinene, the main component of Nutmeg oil is not reproductively toxic.
Systemic Effects
· Acute Toxicity: Acute oral LD50 has been reported as 2.62 g/kg and 2.6 g/kg in rats, 5.6 g/kg in mice and 6 g/kg in hamsters; acute dermal LD50 in rabbits >10 mL/kg.
· Antioxidant/pro-oxidant activity: Nutmeg oil has demonstrated significant antioxidant activity in vitro and in vivo. It showed potent DPPH radical scavenging activity, with an IC50 of 0.13 mL/Ml.
· Carcinogenic/anti carcinogenic potential: Nutmeg oil has both rodent carcinogens and anticarcinogens. Methyl eugenol and safrole are carcinogenic whereas (þ)-limonene and myristicin display anticarcinogenic activity. Nutmeg oil was not mutagenic in the Ames test, and did not produce CA in Chinese hamster fibroblasts. Its dose-dependently inhibited aflatoxin B1-induced adducts in calf thymus DNA, in the presence of rat liver microsomes. Also, Nutmeg oil induced glutathione transferase in the mouse liver.
· Drug interactions: It is a weak inhibitor of MAO and not at a level suggestive of drug interaction.
ECOLOGICAL INFORMATION
· Ecotoxicity: No data available
· Bioaccumulation: No data available
· Mobility in soil: No data available
· Persistence and degradability: No data available
· PBT and vPvB assessment: No data available
· Avoid direct exposure into water streams and ground water sources.
