PS-Davana1.pdf
Botanical Name: Artemisia pallens Common name: Damar, Indhana Read More
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Botanical Name: |
Artemisia pallens |
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Common name: |
Damar, Indhana, Sage Brush, Worm wood |
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Plant family: |
Asteraceae |
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Genus: |
Artemisia |
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Appearance/Color: |
Pale yellow, clear, transport, mobile liquid. |
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Odor: |
Rich, penetrating, strongly boozy mysterious, and sweet/herbaceous body notes; has balsamic warm wood and bittersweet undertones and a slight camphoraceous note. |
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Blends With: |
Geranium, grapefruits, cedar wood, caraway, coriander and chamomile. |
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Origin: |
India |
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Source: |
Leaves |
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Method of Extraction: |
Steam Distillation |
Genus Artemisia (Asteraceae) popularly known as “Sage Brush” or “Worm wood” is bitter aromatics. Artemisia is the largest genus comprising of 400 species widely distributed in South Africa and South America, and 34 species are found in India. This genus is named in honor of Artemis the Greek goddess of chastity. Some of them are sources of volatile oils. Sesquiterpene lactones are known to be present in almost all species.
It is commercially cultivated for its fragrant leaves and flowers. It grows from seeds and cuttings and reaches maturity in four months. The plant is woody in the lower part of the stem, but with yearly branches. Davana is mostly cultivated in the red soil regions in South India. It comes up very well in rich loamy soils. Davana is an annual herb, family compositor, requiring about four months to reach maturity, at which it attains a height of about around one and half feet. Season is very important when the crop is grown for production of oil.
It has been widely used in Indian folk medicine for the treatment of diabetes mellitus. This plant is accredited with antihelmintic, antipyretic and tonic properties and also considered as a good fodder. The oil possesses antispasmodic, antibacterial, antifungal and stimulant properties. The plant has been screened for the antimicrobial, antidiabetic, antinociceptive and wound healing activity. The current study deals with the Phytochemical and Pharmacological of Artemisia pallens.
Davana Essential Oil in Pharma
The leaves and flowers yield an essential oil known as oil of Davana. Several species yield essential oil and some are used as fodder, some of them are a source of the valuable antihelmintic drug santonin. Davana blossoms are offered to Shiva, the God of Transformation, by the faithful, and decorate his altar throughout the day. Davana has been widely used In Iraqi and Indian medicine for the treatment of diabetes mellitus. Oral administration of an aqueous/methanolic extract from the aerial parts of the plants was observed to reduce diabetes in glucose?fed hyperglycemic and alloxan-treated rabbits and rats.
· Davana oil is emotionally balancing and calming, aids in calming down anxiety.
· Davana oil is used in making perfumes of sweet and fruity fragrances.
· When applied on the skin, Davana is said to smell differently on different persons. This peculiar property is highly valued in high class perfumery to create fragrances with truly individual notes.
· Davana leaves and stalks are used in making bouquets, garlands, fresh or dry flower arrangements.
· Davana is massaged over lower abdominal area to stimulate moon cycle.
· Davana oil is soothing to rough, dry, chapped skin, skin infections and cuts.
· Oral administration led to significant blood glucose lowering effect.
· Artemisia pallens is a preferred food for the larvae of a number of butterfly species.
Essence of Davana Essential Oil
Artemisia species are invariably found as small fragrant shrubs or herbs and most of them yield essential oils. Some of these oils are used as medicine such as vermifuge, stimulant and in perfumery, etc. The leaves of some species are used as culinary herbs. The plants themselves are popular among gardeners as cultivated ornamentals.
COMMON USAGE
· Heals wounds
· Fights infections
· Emmenagogue
· Eases breathing
· Relaxes the body
· Speeds up healing
Ingredients:
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S.No |
Key Constituents |
Strength (%) |
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1 |
(Z)-Davanone |
38.0 |
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2 |
Nerol |
10.0 |
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*Tentative identification |
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3 |
Unidentified furans |
6.0 |
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4 |
(E)-Davanone |
5.0 |
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5 |
Geraniol |
5.0 |
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6 |
(z)-hydroxy-davanone |
3.0 |
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7 |
Isodavanone |
3.0 |
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8 |
Davanic acid |
2.5 |
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9 |
Cinnamyl cinnamates |
2.0 |
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10 |
(E)-hydroxy-davanone |
2.0 |
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11 |
Oxo-nerolidol |
2.0 |
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12 |
Artemone |
1.5 |
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13 |
Davana ether |
1.5 |
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14 |
Nor-davanone |
1.5 |
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15 |
(E)-davanonafuran |
1.0 |
TOXICOLOGICAL INFORMATION
Safety Summary
· Hazardous No Data
· Contraindications Not Known
Organ-specific effects
· Adverse skin reactions: Undiluted davana oil was moderately irritating to rabbits, but was not irritating to mice or pigs; tested at 4% on 25 volunteers it was neither irritating nor sensitizing. It is non-phototoxic.
Systemic effects
· Acute toxicity non-toxic: Davana oil acute oral LD50 in rats>5 g/kg; dermal LD50 in rabbits>5 g/kg.
· Subacute and subchronic toxicity
When davana oil was consumed by male rats at 18.1 mg/kg/day, no adverse effects were observed on growth, food consumption, hematology, blood chemistry, liver weight, kidney weight, or the microscopic or gross appearance of major organs.
· Carcinogenic potential: No information found for davana oil, but it contains the down carcinogens.
ECOLOGICAL INFORMATION
· Toxicity Very toxic to aquatic life with long lasting effects. No aquatic toxicity data available for the substances. The product must not be allowed to run into drains or waterways.
· Persistence & degradability Biodegradability: no degradability data is available; the substance is considered as not degrading quickly.
· Bioaccumulation Potential No additional data available.
· Mobility in soil No additional data available.
Results of PBT and vPvB Assessment No additional data available.
