EU_Declaration70.pdf
Botanical Name: Syzgium aromaticum L. Common name: Kanafuru, Plant Read More
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Botanical Name: |
Syzgium aromaticum L. |
|
Common
name: |
Kanafuru, |
|
Plant family: |
Myrtaceae |
|
Genus: |
Syzgium |
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Appearance/Color: |
A clear pale yellow to yellow liquid of medium
consistency. |
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Odor: |
A middle note of medium aroma, Clove Bud Essential Oil smells
like the actual spice. |
|
Blends With: |
Blends well with other spice oils including Cinnamon Bar,
Nutmeg, Citronella, Grapefruit, Lemon, Orange, Peppermint, Rosemary and Rose. |
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Origin: |
India |
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Source: |
Dried Flower Buds |
|
Method of
Extraction |
Supercritical CO2 Extraction |
Supercritical
CO2 extraction is an efficient separation method, to separate active
ingredients from plant material. Supercritical solvent extraction is one of the
gentlest, most flexible, dynamic and nature friendly techniques used for the
extraction of spices, herbs and flowers using food grade CO2. These
are the products extracted at ambient temperatures and at high pressures to
avoid loss of aroma and degradation of actives. Apart from being solvent
residue free, supercritical fluid extraction is a green process, highly rated
for its eco-friendliness. The low viscosity and high diffusivity of
supercritical fluid enhances the penetrating power based on the high mass
transfer of solutes into the fluid.
Supercritical
extraction using CO2 is considered organic compatible and widely
used in the manufacturing of organic certified products. Kancor, with its
global sourcing capabilities, more than two decades of expertise in CO2
extraction and wide range of products, offers an edge over others in this world
of discerning tastes. Supercritical CO2 extraction is known for
producing a high-quality product primarily because the CO2 gas can
reach its supercritical point at pressures and temperatures that don’t damage
the cannabinoids and terpenes being harvested.
One of the earliest known spices
in trade, the dried, aromatic flower buds produced by this medium-sized tree
are familiar to many of us as a common kitchen spice. Clove contains several
volatile oils, the most significant of which is eugenol that comprises up to
90% of the total oil produced. Eugenol has numerous medical and commercial
applications and continues to be extracted primarily from clove buds, though it
can also be extracted from the leaves of the clove tree and from some other
plants, such as allspice (Pimenta dioica), in smaller quantities.
Clove was originally found only
on the Maluku Islands of Indonesia, but in the 17th century fierce competition
between warring European nations that sought control of the spice trade
eventually led to clove trees being transported all over the world for
cultivation.
The historical importance of
clove in international trade means it is now grown in numerous locations
throughout the tropics including Indonesia, Zanzibar, Madagascar, Sri Lanka and
parts of the Caribbean. More recently, clove production has begun in the
Brazilian state of Bahia. Clove grows best on tropical mountain slopes at lower
elevations as part of a mixed forest. Many of the islands to which they are
native are volcanic.
Clove is most famous for its use
as a spice and has been valued for centuries for the unique flavor and
preservative qualities it can impart to food. In Europe, whole cloves are
commonly pressed into red meats before cooking and are also included in many seasonal
dishes, such as mulled wine at Christmas. Clove is an important ingredient in
many spice mixes, including most garam masala and Chinese five-spice mixes.
Clove Essential Oil in Pharma
Although best known in Asian
medical systems such as Ayurveda, clove has numerous applications in
traditional and modern medicine with a broad range of different therapeutic
effects having been reported. Its confirmed antimicrobial, antifungal,
antiviral and anti-inflammatory properties have made it popular for treating a
variety of different infections, for example as a gargle for sore throats or
for cleaning minor wounds. It is also commonly used for digestive
complaints because of its antispasmodic action, and some studies report that
clove can reduce the likelihood of gastric ulcer formation. Modern
research interest into the uses and efficacy of clove is high, with numerous
studies investigating it for anti-carcinogenic, chemoprotective and other
properties. Some studies have also shown that clove can work synergistically
with other medicinal plants to fight bacterial infection more effectively.
Essence of Clove Essential Oil
Clove oil is an ingredient in
several popular perfumes and the source of raw materials used for manufacturing
fragrances and flavorings. Oils are often extracted from the leaves of the tree
as well as the flower buds for fragrance manufacturing purposes. Clove was also
formerly used to synthesize vanillin - artificial vanilla flavoring. It is an
main ingredient of Indian spices.
Clove is well known as a
traditional home remedy for mild toothache and inflammation of the mouth
because of its analgesic and antiseptic effects. It has also been traditionally
used to treat bad breath and tooth decay and has a long history of use in
dentistry. Eugenol, the primary constituent extracted from clove, is still used
in several dental products and processes today.
COMMON USAGE
·
Prevents dental problems
·
Rejuvenates skin
·
Improves immunity
·
Reduces anxiety and stress
·
Cures respiratory ailments
·
Lowers headache
·
Eliminates earaches
·
Aids in digestion
·
Cures nausea
·
Stimulates blood circulation
·
Acts as blood purifier
·
Prevents premature ejaculation
·
Controls sugar level
·
Cures cholera
·
Works as cancer preventive agent
Ingredients:
|
S.No |
Key Constituents |
Strength (%) |
|
1 |
Eugenyl acetate |
0.6-01.7 |
|
2 |
Eugenol |
63.5-56.7 |
|
3 |
b-caryophyllene |
01.04-0.2 |
|
4 |
Isoeugenol |
01.04-0.2 |
|
5 |
a-caryophyllene |
0.05-1.12 |
|
6 |
Methyl-eugenol |
0-0.2 |
TOXICOLOGICAL
INFORMATION
Safety Summary
·
Hazardous: Drug interaction; may contain
methyl-eugenol; may inhibit blood clotting; embryotoxicity; skin sensitization
(moderate risk); mucous membrane irritation (moderate risk). Cautions (oral):
May interact with pethidine, MAOIs or SSRIs. Anticoagulant medication, major
surgery, peptic ulcer, hemophilia, other bleeding disorders.
·
Contraindications: Hypersensitive, diseased or
damaged skin, children under 2 years of age. Maximum dermal use level.
Maximum dermal
use level (based on methyl-eugenol content)
|
EU |
0.1% |
|
IFRA |
0.2% |
|
Tisserand and young |
10% |
Maximum dermal
use level (based on eugenol content)
|
EU
NO |
Legal
limit |
|
IFRA |
0.4% |
|
Tisserand and young |
0.4% |
Organ Specific Effects
·
Adverse Skin Reactions: skin sensitizing
potency, clove leaf oil was a weak sensitizer, with a similar potency to
eugenol.
·
Cardiovascular effects: Eugenol is a
powerful inhibitor of platelet aggregation, an essential step in the blood
clotting cascade.
Systemic Effects
·
Acute Toxicity
o Oral
route: DL50 = 2650 mg/kg
o
Dermal route: DL50 > 5000 mg/kg
·
Respiratory sensitization: Not applicable under
normal use.
·
Germ cell mutagenicity: Cause for concern owing
to the possibility that it may induce heritable mutations in the germ cells of
humans.
·
Carcinogenicity: IARH: No component of this
product present at levels greater than or equal to 0.1% is identified as
probable, possible or confirmed human carcinogen by IARC. ACGIH: No component
of this product present at levels greater than or equal to 0.1% is identified
as probable, possible or confirmed human carcinogen by IARC.
·
NTP: No component of this product present at
levels greater than or equal to 0.1% is identified as probable, possible or
confirmed human carcinogen by IARC.
·
OSHA: No component of this product present at
levels greater than or equal to 0.1% is identified as probable, possible or
confirmed human carcinogen by IARC.
·
Reproductive toxicity: Not specified
·
STOT-single exposure: Not specified
·
STOT-related exposure: Not specified
·
Aspiration hazard: Not specified
ECOLOGICAL
INFORMATION
·
Toxicity
Harmful to aquatic life with long lasting effects. The product must not be
allowed to run into drains or waterways.
·
Substances classified as category 1 Acute
toxicity
·
Persistence and degradability: Biodegradation is
expected
·
Bio-accumulative potential Bioaccumulation is
unlikely
·
Mobility in soil Unknown
