EU_Declaration57.pdf
Botanical Name: Myristica Fragrans Common name: Nutmeg Plant fa Read More
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Botanical Name: |
Myristica
Fragrans |
|
Common name: |
Nutmeg |
|
Plant
family: |
Myristicaceae |
|
Genus: |
Myristica |
|
Appearance/Color: |
Colorless to slight yellow color liquid having clear and thin consistency |
|
Odor: |
It has
a sweet, spicy scent reminiscent of nutmeg with medium aroma at middle note |
|
Blends With: |
Lavender, Bay, Orange, Geranium, Clary Sage, Rosemary, Lime,
Petitgrain, Mandarin and Coriander |
|
Origin: |
Sri
Lanka |
|
Source: |
Aril (pericarp) which surrounds the ripe seed |
|
Method
of Extraction: |
Supercritical
CO2 Extraction |
Supercritical
CO2 extraction is an efficient separation method, to separate active
ingredients from plant material. Supercritical solvent extraction is one of the
gentlest, most flexible, dynamic and nature friendly techniques used for the
extraction of spices, herbs and flowers using food grade CO2. These
are the products extracted at ambient temperatures and at high pressures to
avoid loss of aroma and degradation of actives. Apart from being solvent
residue free, supercritical fluid extraction is a green process, highly rated
for its eco-friendliness. The low viscosity and high diffusivity of
supercritical fluid enhances the penetrating power based on the high mass
transfer of solutes into the fluid.
Supercritical
extraction using CO2 is considered organic compatible and widely
used in the manufacturing of organic certified products. Kancor, with its
global sourcing capabilities, more than two decades of expertise in CO2
extraction and wide range of products, offers an edge over others in this world
of discerning tastes. Supercritical CO2 extraction is known for
producing a high-quality product primarily because the CO2 gas can
reach its supercritical point at pressures and temperatures that don’t damage
the cannabinoids and terpenes being harvested.
Myristica fragrans is
commonly named nutmeg or mace. It is an aromatic evergreen tree with spreading
branches and a yellow fleshy fruit similar in appearance to an apricot or
peach. The nutmeg fruit is pendulous and
similar in presentation to a peach. When fully mature, it splits in two,
exposing a crimson-colored aril. This is the mace which surrounds the nutmeg
pit. Mace is a vibrant red-colored seed husk covering (aril).
Mace Essential Oil has a history of medical
use in combination with nutmeg. It has progressed over time and is added to
soaps, perfumes and it is also used as a cooking ingredient. It smells like and
is very close to nutmeg in its makeup. Its analgesic properties also make it
useful for treating muscle fatigue and arthritis.
Mace Essential Oil in Pharma
The essential oil derived from
Mace is the most efficacious. The oil is a potent brain booster. It increases
concentration and relieves stress. Mace is an excellent liver tonic. It
dissolves kidney stones and prevents infection. The herb is also beneficial for
the heart as it stimulates blood circulation. Mace’s anti-inflammatory
properties are used to treat joint and muscle aches.
The seed of nutmeg is rich in
essential oils. It is a bitter, astringent, spicy herb that acts as a warming,
digestive tonic. It controls vomiting and relaxes spasms. When applied
externally, it has an antiinflammatory effect. Nutmeg is also said to have
stimulant, carminative and aphrodisiac properties. The seed is taken internally
in the treatment of diarrhoea, dysentery, vomiting, abdominal distension,
indigestion and colic. Externally, the seed is used to treat toothache,
rheumatic and abdominal pains (including labour pains). Some caution is advised
- taken in excess the seed can cause severe headache, nausea, dizziness and
delirium. The seed is used in Ayurveda to treat poor digestion, insomnia,
urinary incontinence and premature ejaculation.
Essence of Mace Essential Oil
Nutmeg contains 25–30% fixed oils
and 5–15% volatile oils (camphrene, eugenol, etc.), and also other molecules
such as myristic acid, myristicin, and lignin compounds. Among these molecules,
eugenol is widely used in dentistry, and is very effective in antibacterial
activity against oral bacteria. Nutmeg essence is mostly used to alter spicy
notes. It is sometimes added to eaux de Colognes and eaux de toilettes for men.
Used as a flavor enhancer in mashed potatoes, soups, baked or cooked dishes,
candies, chewing gum, beverages and breakfast cereal.
COMMON
USAGE
·
Analgesic
·
Anti-rheumatic
·
Antiseptic
·
Anti-spasmodic
·
Carminative
·
Digestive
·
Laxative
·
Stimulant
and tonic
·
Stimulate
appetite
·
Assisting
the reproductive system
Ingredients:
|
S.No |
Key Constituents |
Strength (%) |
|
1 |
sabinene |
45.5 |
|
2 |
a-Pinene |
15.2 |
|
3 |
1,8-Cineoleþ(þ)-limonene |
7.0 |
|
4 |
Myristicin |
5.9 |
|
5 |
Terpinen-4-ol |
4.5 |
|
6 |
a-Terpineneþp-cymene |
3.5 |
|
7 |
a-Phellandrene |
3.2 |
|
8 |
Elemicin |
3.1 |
TOXICOLOGICAL INFORMATION
Safety Summary
·
Hazards:
Potentially carcinogenic, based on safrole and methyleugenol content; may be
psychotropic.
·
Respiratory sensitization: Breathing high
concentrations of vapor may cause anesthetic effects.
Safety
advice
Recommended maximum dermal use of 2% for the
Sri Lankan oil and a maximum oral dose of 73 mg based on 1.9% safrole and 0.2%
methyleugenol content, and a dermal maximum of 4.1% and a maximum oral dose of
146 mg for the Sri Lankan oil based on 0.7% safrole and 0.2% methyleugenol.
These are based on dermal limits of 0.05% and 0.02%, and oral dose limits of
0.025 and 0.01 mg/kg for safrole and methyleugenol, respectively.
Organ Specific Effects
·
Adverse skin reaction: Undiluted mace oil was moderately irritating
to rabbits, but was not irritating to mice or pigs; tested at 8% on 25
volunteers it was neither irritating nor sensitizing. It is non-phototoxic.
·
Neurotoxicity: Psychotropic effects have been reported for
nutmeg in high doses. Myristicin and elemicin are thought to be responsible,
but other synergistic elements may need to be present for a psychotropic effect
to take place.
Systemic
Effects
·
Acute
Toxicity: Mace oil acute
oral LD50 in rats 3.64 g/kg; acute dermal LD50 in rabbits >5 g/kg.
·
Carcinogenic/anti carcinogenic potential: No data was found for mace oil. Safrole and
methyleugenol are carcinogenic if the dose is sufficiently high; (þ)-limonene
and myristicin display anticarcinogenic activity.
ECOLOGICAL
INFORMATION
Toxicity
·
Acute fish toxicity (LC50 / 96 HOUR) – No
data available
·
Toxicity to aquatic plants – No data
available
·
Toxicity to microorganisms – No data
available
·
Toxicity threshold – No data available
·
Persistence and degradability Biodegradation is
expected
·
Bio-accumulative potential Bioaccumulation is
unlikely
Avoid exposure to marine environments and waterways.
