Zedoaria Essential Oil

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Product Details

Botanical Name:	Curcuma Zedoaria
Common name:	Zedoary, White turmeric, Temu putih
Plant family:	Zingiberaceae
Genus:	Curcuma
Appearance/Color:	Golden yellow viscous liquid
Odor:	It has a warm-spicy, woody & camphoraceous cineolic odor
Blends With:	Sandalwood
Origin:	India
Source:	Rhizomes
Method of Extraction:	Steam Distillation

Plants of ginger family (Zingiberaceae) have been frequently and widely used as spices and in traditional systems of medicine practiced in many Asian countries, and their medicinal functions have been broadly discussed and accepted in many traditional recipes. The Zingiberaceae plants contain several volatile and essential oils including terpenoids, phenylpropanoids, flavonoids, and sesquiterpenes, which has reported antitumour activity. As plants of Zingiberaceae family are considered safe for human consumption, these species are excellent candidates for development of novel chemotherapeutics. Traditionally, curcuma drugs called “Ukon” and “Gajutsu” in Japanese have been used in oketsu syndromes (caused by the obstruction of blood circulation) in Chinese medicine. Various antineoplastic compounds have also been isolated from curcuma species.

Curcuma zedoaria, a medicinal tuber plant belonging to this family, is a close relative of Curcuma longa from which the curcumin is isolated. Various parts of Curcuma zedoaria are used in Ayurveda and other folk and tribal system of medicines. Curcuma zedoaria is a constituent of a wide variety of ayurvedic preparations like Dasamularishtam, Valiya Rasnadi Kashayam, and so forth. The rhizome is used for curing stomach diseases, toothache, blood stagnation, leucoderma, tuberculosis, enlargement of spleen, and for promoting menstruation in traditional medicine in Asia. Anti-inflammatory activity, antifungal activity, antiulcer activity, antimicrobial effect, hepatoprotective activity, antiamoebic effect, of this plant rhizome have been reported. The Curcuma zedoaria rhizome is termed Ezhu in Chinese and is extensively used in traditional Chinese medicine to treat various ovarian and cervical cancers. Curdione isolated from this plant has been found to inhibit prostaglandin E2 production and cyclooxygenase-2 expression, both of which are implicated in inflammation and carcinogenic process.

DISCLAIMER

The complete range of conditions or methods of use are beyond our control therefore we do not assume any responsibility and expressly disclaim any liability for any use of this product. Information contained herein is believed to be true and accurate however, all statements or suggestions are made without warranty, expressed or implied, regarding accuracy of the information, the hazards connected with the use of the material or the results to be obtained from the use thereof. Compliance with all applicable federal, state, and local laws and local regulations remains the responsibility of the user.

The FDA has not evaluated the statements on this website. No claims are made by Venkatramna Industries as to the medicinal value of any products from vriaroma.com or by us. The information presented here is for educating our customers about the traditional uses of essential oils and is not intended to diagnose, treat, cure, or prevent any disease. You are responsible for understanding the safe application of these products. If you have any questions, please call or email us for further information.

As per NAHA guidelines, New Directions Aromatics (NDA) does not recommend the ingestion of essential oils. It is imperative to consult a medical practitioner before using Essential Oils for therapeutic purposes. Pregnant and nursing women and those taking prescription drugs are especially advised not to use this product without the medical advice of a physician. The oil should always be stored in an area that is inaccessible to children, especially those under the age of 7.

Zedoary has been used in the traditional system of medicine in India and Southwest Asia in treating many human ailments and is found to possess many biological activities. The rationale of the present study was to isolate, identify, and characterize antitumour principles from the rhizomes of Curcuma zedoaria, to assess its cytotoxic effects on human and murine cancer cells, to determine its apoptosis inducing capacity in cancer cells, and to evaluate its tumour reducing properties in in vivo mice models.

Zedoaria Essential Oil in Pharma

C. zedoaria is a well-known ethnomedicinal plant that is also used in Ayurveda. Its use in the Indian traditional folk medicine is also well documented. Below are different parts of C. zedoaria which have different applications in traditional systems of medicine.

Plant parts	Traditional uses
Oil of rhizome	Stomachic, emmenagogic, vomiting, menstrual haematometra
Fresh roots	Treatment of leucorrhoeal discharge
Tuber juice	Treatment of worms in children
Powdered rhizome	Antiallergant
Leaf juice	Treatment of dropsy
Leaf juice	Treatment of leprosy
Leaf paste	As plasters in lymphangitis, furunculosis

Essence of Zedoaria Essential oil

Zedoary root is actually a rhizome with a thin brown skin and a bright orange, hard interior. It’s smell is similar to turmeric and mango. Because of the mango-like fragrance, zedoary is called amb halad in many Indian languages (amb means mango). It is sold as a powder, or dried and sliced with a gray surface with a yellow to gray-white interior. It is a part of great Indian spices used to flavoring in the foods.

COMMON USAGE

· Digestive Aid

· Respiratory Problems

· Relieves Inflammation and Pain

· Antimicrobial activity

· Anti-inflammatory and painkiller property

· Anti-allergic activity

· Antibacterial and antifungal

· Antinyeri medicine

· Ulcer medicine

· Anti-cancer

· Lowering blood sugar levels

Ingredients:

S.No	Key Constituents	Strength (%)
1	Curzerenone	22.3
2	1,8-Cineole	15.9
3	Germacrone	9.0
4	Camphor	7.8
5	b-Pinene	5.9
6	Curzerene	5.0
7	a-Pinene	3.7
8	Isoborneol	2.1
9	Camphene	1.9
10	b-Elemene	1.5
11	(Z)-b-Elemenone	1.5
12	Germacrene	1.2
13	(þ)-Limonene	1.2
14	2-Nonanol	1.0

TOXICOLOGICAL INFORMATION

Safety Summary

· Hazards: May interfere with gestation.

· Cautions: Pregnancy, breastfeeding.

Organ Specific Effects

· Adverse skin reaction: No information found.

· Reproductive toxicity: Chinese zedoary oil was administered to pregnant mice on gestational days 4–6 as a 1% or 10% aqueous solution with Tween 80 as an emulsifier. Ip doses of essential oil were 156, 310 and 625 mg/kg on gestational days 2–4, and sc doses were 600 and 900 mg/kg/day on gestational days 4–6. Prevention of implantation was dose-dependently successful, ranging from 10% to 80% ip, and from 70% to 90% sc. The oil prevented 77% of pregnancies in female rats when given ip at 300 mg/kg on gestational days 7–9. It prevented 16% and 100% of pregnancies in female rabbits when administered intra-vaginally at 60 or 400 mg/kg/day on gestational days 5–9 and 2–4, respectively. The oil was steam distilled, but no compositional details were given. Ethanol extracts *Isomer not specified and decoctions of zedoary rhizomes also have anti fertility effects. Subsequent research shows a strong link between the embryo toxic effect of zedoary oil and its anti angiogenic action.

· Hepa totoxicity: Single oral doses of 12.5, 25 or 50 mg/kg of either germacrone or curcumenol showed dose dependent protection against liver injury induced in mice by D-galactosamine /lipopolysaccharide or TNF-a.

Systemic Effects

· Acute Toxicity: No data found.

· Carcinogenic/anti carcinogenic potential: A Chinese hydro distilled zedoary oil was cytotoxic to mouse melanoma B16BL6 cells, and to human hepatoma SMMC-7721 cells. Zedoary oil also inhibited angiogenesis in mice. The essential oil analyzed by Mau et al 2003 was cytotoxic to human leukemia HL-60 cells, with an IC50 of 500 ppm. a- Caryophyllene and b-elemene display anti carcinogenic activity. Germacrone dose dependently inhibited the growth of human breast cancer cells in vitro. Curzerenone has been used as an anticancer agent in China.